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Cake day: March 13th, 2024

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  • Lots of stretching here. The paper uses simulations of microtubules to show quantum effects when tryptophan residues are excited by UV light. The paper only did simulations of microtubules, and those simulations did not include the bends and many many dynein molecules found on microtubules. The reason this is important is that researchers have been hitting every biomolecule with UV excitation for decades, including microtubules, and have never observed this effect.

    A key finding missing from this video is that microtubules are dynamic. They are constantly disassembling and reassembling and recycling components. This occurs at very short timescales. Also, they do not bridge cell membranes. If information is passing through networks of microtubules, it is constantly disrupted and not affecting other cells. Synapses do handle cell-cell information transfer (where the role of microtubules is already well studied and not quantum in nature). Why would quantum microtubule information be limited to a single cell? Maybe it could influence coordinated assembly and disassembly at the termini, but the authors offer no evidence that there is any chemical effect of this quantum phenomenon, which would be required to change anything about how those enzymes behave.

    We already know of a mechanism by which information is transported across microtubules: physical transport of signalling molecules. They are walked (quite literally, dynein is cool) along the microtubules to different sites in the cell. No quantum effects needed to explain this phenomenon.


  • Go to pubmed. Type “social media mental health”. Read the studies, or the reviews if you don’t have the time.

    The average American teenager spends 4.8 hours/day on social media. Increased use of social media is associated with increased rates of depression, eating disorders, body image dissatisfaction, and externalizing problems. These studies don’t show causation, but guess what, we literally cannot show causation in most human studies because of ethics.

    Social media drastically alters peer interactions, with negative interactions (bullying) associated with increased rates of self harm, suicide, internalizing and externalizing problems.

    Mobile phone use alone is associated with sleep disruption and daytime sleepiness.

    Looking forward to your peer-reviewed critiques of these studies claiming they are all “just vibes.”







  • I remember hearing this argument before…about the Internet. Glad that fad went away.

    As it has always been, these technologies are being used to push us forward by teams of underpaid unnamed researchers with no interest in profit. Meanwhile you focus on the scammers and capitalists and unload your wallets to them, all while complaining about the lack of progress as measured by the products you see in advertisements.

    Luckily, when you get that cancer diagnosis or your child is born with some rare disease, that progress will attend to your needs despite your ignorance if it.




  • We are not in a recession. The problems with wage stagnation are not some temporary hiccup in the economy. It is a systemic problem. Stop conflating the two, complaining that a macroeconomic term with a very specific meaning isn’t defined the way you want it to be. Stop expecting the problem to heal itself if the fed lowers rates or taxes get nudged up or down or whatever. We know how to fix wage stagnation because we have done it before. Regulation. Labor protections. Minimum wage increases. Wage stagnation occurs in the absence of these things, and they can only be done by Congress.


  • The campaign is not the government. The meme manager will have literally 0 influence on foreign policy.

    Changes to foreign policy are more likely to occur if you direct all this energy to the 30%+ of Americans that fully support an unfettered Israeli military, rather than disparage the only US president in recent history to openly criticize Israel during wartime. In the context of US-Israel relations, Biden is waaaay outside the norm in pushing back against Israeli interests.